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Projects: LiSyM-Krebs Partnering
Institutions: Roche Pharma AG
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network
Institutions: Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie
Projects: LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM PALs, LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, DEEP-HCC network
Institutions: Zentrum für Informationsdienste und Hochleistungsrechnen (ZIH), Technische Universität Dresden
https://orcid.org/0000-0003-0137-5106The clinical department of Prof. Dr. med Daniel Seehofer performs more than 200 surgical interventions on the liver annually. Therefore, the group has access to a broad variety of liver tissues as well as corresponding patient, clinical laboratory and characterization data. I lead the experimental work group which has a longstandind expertise in the isolation, characterization and application of primary human liver and hepatoma cells. These cells as well as data generated from established liver ...
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM-Krebs Partnering
Institutions: LiSyM programme directorate
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network, SMART-NAFLD
Institutions: Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM network, LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network
Institutions: INRIA (French National Institute for Research in Computer Science and Control), Leibniz-Institut für Arbeitsforschung (IfADo)
Projects: LiSyM-Krebs Partnering
Institutions: Hochschule Niederrhein - Institut für Modellbildung und Hochleistungsrechnen
Projects: LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), LiSyM PALs, LiSyM network, LiSyM-Krebs Partnering
Institutions: HITS gGmbH
https://orcid.org/0000-0002-8683-7084Data management and standardization expert for systems biology and systems medicine, responsible for the data management user requirements and user contacts within the German LiSyM network (Liver Systems Medicine: http://lisym.org/) and associated to the FAIRDOM team. Involved in different standardization initiatives and committees, i.e. COMBINE (http://co.mbine.org), ISO/TC 276 Biotechnology (https://www.iso.org/committee/4514241.html), European COST action CHARME (http://www.cost-charme.eu) and ...
We are building digital pathology application for biomarker analysis in epidemiological and clinical studies. This includes management and supporting the creation of very large data collections from whole-slide imaging. In large epidemiological studies AI image analysis is validated yielding clinically useful biomarker analysis for translating research projects into applications.
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM PALs, LiSyM-Krebs Partnering, C-TIP-HCC network
Institutions: Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University
Projects: LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, DEEP-HCC network
Institutions: Universitätsklinikum Dresden - Medizinische Klinik I, Bereich Gastroenterologie & Hepatologie, Zentrum für Informationsdienste und Hochleistungsrechnen (ZIH), Technische Universität Dresden
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network
Institutions: Leibniz-Institut für Arbeitsforschung (IfADo)
Projects: LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, C-TIP-HCC network
Institutions: Universität Leipzig - Institute for Computer Science (Bioinformatics), Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie
Projects: LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering
Institutions: Charité - Universitätsmedizin Berlin, Institute of Biochemistry, Computational Systems Biochemistry Group
Projects: LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM)
Institutions: LiSyM programme directorate
Projects: LiSyM-Krebs Partnering, LiSyM network, LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Scientific Leadership Team (LiSyM-LT), Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, C-TIP-HCC network
Institutions: German Cancer Research Center (DKFZ), Division of Systems Biology of Signal Transduction
Detailed Profile here
Projects: LiSyM PALs, Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), LiSyM network, LiSyM-Krebs Partnering
Institutions: Humboldt-Universität zu Berlin - Institute for Theoretical Biology (ITB)
https://orcid.org/0000-0003-1725-179XWe are investigating liver metabolism and function with the help of computational models and methods.
Group Leader Dr. Matthias König
Institute for Theoretical Biology Humboldt-University Berlin Philippstraße 13, 10115 Berlin, Germany phone +49 30 2093-98435 koenigmx@hu-berlin.de https://www.livermetabolism.com
The König group works on computational modeling, data science, data management, bioinformatics methods and machine learning on ...
Projects: LiSyM PALs, LiSyM network, LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM-Krebs Partnering, Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, DEEP-HCC network, C-TIP-HCC network, Default Project
Institutions: HITS gGmbH
https://orcid.org/0000-0003-3540-0402I am a researcher at the Scientific Databases and Visualization Group at Heidelberg Institute for Theoretical Studies (HITS) , one of the developers of SabioRK - System for the Analysis of Biochemical Pathways - Reaction Kinetics (http://sabiork.h-its.org/) . I am working on design and maintenance of the information systems to store, query and analyse systems biology data; definition and implementation of methods for the integration of data from multiple sources. In SySMO-DB project ...
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering
Institutions: Bayer AG
Projects: LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, C-TIP-HCC network
Institutions: Saarland University Hospital - Department of Medicine II
Projects: LiSyM-Krebs Partnering
Institutions: Technical University Munich - Klinikum rechts der Isar
I lead scientific research in the Biobank of the Department of General, Visceral and Transplant Surgery in Ludwig Maximilians University in Munich.
Projects: LiSyM-Krebs Partnering
Institutions: Universitätsklinikum Schleswig-Holstein, Campus Lübeck - Medizinische Klinik I
Projects: The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM PALs, LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, SMART-NAFLD, DEEP-HCC network, Forschungsnetzwerk LiSyM-Krebs
Institutions: Universität Leipzig - Medizinische Fakultät - Institut für Biochemie, Universität Leipzig - Sächsischer Inkubator für Klinische Translation (SIKT)
Group leader of the junior group: The Hedgehog Signalling Pathway (LiSyM-JGMMS)
Projects: Project Management PTJ, LiSyM network, LiSyM-Krebs Partnering
Institutions: PTJ - Projektträger Jülich - Forschungszentrum Jülich GmbH
I am a trained computer scientist (Habilitation) and physicist (Diploma). My interest is interactive search for information, as well as preparing data for FAIR reuse, a.k.a curation. Within LiSyM I am coordinator of the data management services.
Projects: LiSyM-Krebs Partnering
Institutions: Leibniz Institute for Natural Product Research and Infection Biology
Former postdoc in the Theoretical Biophysics group headed by Edda Klipp at Humboldt-Universität zu Berlin and member of the LiSyM network, I am now an independent Group Leader at the Technical University of Munich focusing on developing an advanced bioinformatics toolbox for analyzing, integrating, and mining of various omics data in the context of precision medicine as well as molecular disease and patient subtyping.
I am a trained biologist (PhD). Within LiSyM Cancer I am working for the central data management team in the Scientific Databases and Visualization (SDBV) Group at Heidelberg Institute for Theoretical Studies (HITS). Our main purpose is to support the members of the network in FAIR data management by offering 5 systems for data storage and exchange and by helping them using these systems. Before I was involved in the de.NBI project helping the systems biology community and beyond with content ...
Projects: LiSyM-Krebs Partnering, DEEP-HCC network
Institutions: Helmholtz-Zentrum Dresden-Rossendorf
Projects: LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM network, LiSyM-Krebs Partnering, LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), LiSyM Scientific Leadership Team (LiSyM-LT), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM)
Institutions: University of Freiburg - Institute of Physics, LiSyM programme directorate
Projects: LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM network, LiSyM-Krebs Partnering, DEEP-HCC network, Forschungsnetzwerk LiSyM-Krebs
Institutions: Universitätsklinikum Campus Kiel - Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Universitätsmedizin Rostock, Chirurgische Klinik und Poliklinik
Interested in modelling metabolism, predicting metabolic phenotypes and dynamic transitions in metabolism. Also using partially and incompletely characterized models (probabilistic predictions).
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, C-TIP-HCC network
Institutions: University of Freiburg - Institute of Physics
https://orcid.org/0000-0003-4517-1383Postdoc, Andrej Shevchenko's lab , biological mass spectrometry, MPI-CBG, Dresden
Projects: LiSyM-Krebs Partnering, Project Management PTJ
Institutions: PTJ - Projektträger Jülich - Forschungszentrum Jülich GmbH