LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi)

Disorders of the liver show up through changes in blood tests. These blood tests indicate markers for events taking place in the liver. Usually studies of liver tissue cannot be performed: as liver samples would need to be obtained through a liver biopsy, and this procedure is not without risk, therefore these samples are usually unavailable. Complex metabolism models based on existing and new scientific data can simulate changes in the liver caused by disease. They often reveal unknown relationships and interactions clearly. Thus, LiSyM-Pillar IV is developing new computer-aided diagnostic tools. What indicates that diseases are looming? Which tests bring this to light? Do functions also change regionally in the liver?

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