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- Dirk Drasdo
SEEK ID: https://seek.lisym.org/people/94
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LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP) (INRIA (French National Institute for Research in Computer Science and Control)) ; LiSyM network (INRIA (French National Institute for Research in Computer Science and Control)) ; LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF) (INRIA (French National Institute for Research in Computer Science and Control)) ; LiSyM Scientific Leadership Team (LiSyM-LT) (INRIA (French National Institute for Research in Computer Science and Control)) ; LiSyM-Krebs Partnering (INRIA (French National Institute for Research in Computer Science and Control)) ; LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP) (Leibniz-Institut für Arbeitsforschung (IfADo)) ; LiSyM network (Leibniz-Institut für Arbeitsforschung (IfADo)) ; LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF) (Leibniz-Institut für Arbeitsforschung (IfADo)) ; LiSyM Scientific Leadership Team (LiSyM-LT) (Leibniz-Institut für Arbeitsforschung (IfADo)) ; LiSyM-Krebs Partnering (Leibniz-Institut für Arbeitsforschung (IfADo)) ; LiSyM-Krebs (Leibniz-Institut für Arbeitsforschung (IfADo))
Related items
- Projects (6)
- Institutions (2)
- Investigations (0+1)
- Studies (0+1)
- Publications (15)
- Presentations (5+3)
- Documents (0+1)
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Programme: LiSyM-Krebs
Public web page: https://www.ptj.de/projektfoerderung/gesundheitsforschung/lisym-krebs
Organisms: Not specified
LiSyM-Krebs
Programme: LiSyM-Krebs
Public web page: Not specified
Organisms: Homo sapiens
Day-to-day science within the LiSyM is overseen and directed by the the LiSyM Scientific Leadership Team. This coordination team comprises the pillar coordinators and additional LiSyM members, and ensures smooth interaction between multi-skilled groups, often working in different institutions and across significant distances within Germany.
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/who-we-are
Organisms: Not specified
In one in five people with NAFLD, the functioning liver cells, the hepatocytes, are replaced by connective tissue. Eventually this fibrosis becomes irreversible. In this state the liver is like a ‘scar that never heals’. Through it, the liver loses many of its vital functions.
LiSyM-Pillar II wants to know more about which factors promote fibrosis and the conditions under which fibrosis becomes irreversible How can fibrosis be diagnosed as early as possible? Researchers in the pillar are also
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
In chronic diseases, at some point the liver can suddenly stop functioning. This is called acute-on-chronic liver failure, or ACLF. This is the leading cause of death in liver patients and is often provoked by the use of transcription or freely available drugs or alcohol abuse. For this condition we need an effective treatment quickly.
LiSyM-Pillar III researches the factors that contribute significantly to ACLF. What exactly happens then? Are there any early signs that would enable ACLF to be
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Rattus rattus
Abstract (Expand)
Authors: N. Boissier, D. Drasdo, I. E. Vignon-Clementel
Date Published: 29th Nov 2020
Publication Type: Journal
PubMed ID: 33249746
Citation: Int J Numer Method Biomed Eng. 2020 Nov 29:e3422. doi: 10.1002/cnm.3422.
Abstract (Expand)
Authors: Nachiket Vartak, Georgia Guenther, Florian Joly, Amruta Damle‐Vartak, Gudrun Wibbelt, Jörns Fickel, Simone Jörs, Brigitte Begher‐Tibbe, Adrian Friebel, Kasimir Wansing, Ahmed Ghallab, Marie Rosselin, Noemie Boissier, Irene Vignon‐Clementel, Christian Hedberg, Fabian Geisler, Heribert Hofer, Peter Jansen, Stefan Hoehme, Dirk Drasdo, Jan G. Hengstler
Date Published: 19th Jun 2020
Publication Type: Journal
DOI: 10.1002/hep.31422
Citation: Hepatology,hep.31422
Abstract
Authors: Stefan Hoehme, Rolf Gebhardt, JG Hengstler, D. Drasdo
Date Published: 18th May 2020
Publication Type: Misc
Citation:
Abstract
Authors: Adrian Friebel, Tim Johann, Dirk Drasdo, Stefan Hoehme
Date Published: 18th May 2020
Publication Type: Misc
Citation:
Abstract
Authors: Paul Van Liedekerke, Johannes Neitsch, Tim Johann, Enrico Warmt, Ismael Gonzàlez-Valverde, Stefan Hoehme, Steffen Grosser, Josef Kaes, Dirk Drasdo
Date Published: 1st Feb 2020
Publication Type: Journal
DOI: 10.1007/s10237-019-01204-7
Citation: Biomech Model Mechanobiol 19(1):189-220
Creators: Tim Johann, Dirk Drasdo, Stefan Hoehme, Paul Van Liedekerke, Johannes Neitsch
Submitter: Tim Johann
Computational models complement experimental methods in the analysis of tissue organization processes, and play an increasingly important role in systems biology and systems medicine. Creating and parameterizing mathematical models for the simulation of biological tissue dynamics at multiple scales is still a complex and resource-consuming task, which necessitates skills in diverse scientific disciplines. The software TiSim was conceived to facilitate programming, integration and deployment of
...
Creators: Tim Johann, Jieling Zhao, Stefan Hoehme, Dirk Drasdo, Andreas Buttenschön, Noémie Boissier, Géraldine Cellière, Paul Van Liedekerke, Johannes Neitsch
Submitter: Tim Johann
Creators: Tim Johann, Dirk Drasdo, Ayham Zaza, Jieling Zhao, Paul Van Liedekerke
Submitter: Tim Johann