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- Seddik Hammad
SEEK ID: https://seek.lisym.org/people/36
Location:
Germany
Expertise: Animal experimentalist, Imaging and image analysis, Omics
Tools: Animal facility, Microarray analysis, confocal microscopy, Metabolomics
ORCID: Not specified
LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP) (Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University) ; LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF) (Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University)
LiSyM network (Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University) ; LiSyM PALs (Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University) ; LiSyM-Krebs Partnering (Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University)
Related items
- Projects (5)
- Institutions (1)
- Investigations (1+1)
- Studies (1+2)
- Assays (1+5)
- Data files (7+16)
- Publications (53)
- Presentations (24+7)
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Programme: LiSyM-Krebs
Public web page: https://www.ptj.de/projektfoerderung/gesundheitsforschung/lisym-krebs
Organisms: Not specified
In one in five people with NAFLD, the functioning liver cells, the hepatocytes, are replaced by connective tissue. Eventually this fibrosis becomes irreversible. In this state the liver is like a ‘scar that never heals’. Through it, the liver loses many of its vital functions.
LiSyM-Pillar II wants to know more about which factors promote fibrosis and the conditions under which fibrosis becomes irreversible How can fibrosis be diagnosed as early as possible? Researchers in the pillar are also
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
In chronic diseases, at some point the liver can suddenly stop functioning. This is called acute-on-chronic liver failure, or ACLF. This is the leading cause of death in liver patients and is often provoked by the use of transcription or freely available drugs or alcohol abuse. For this condition we need an effective treatment quickly.
LiSyM-Pillar III researches the factors that contribute significantly to ACLF. What exactly happens then? Are there any early signs that would enable ACLF to be
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Rattus rattus
This is a generic project that comprises all LiSyM data management PALs and associated FAIRDOM PALs, as well as the LiSyM data management team.
Programme: LiSyM: Liver Systems Medicine
Public web page: Not specified
Organisms: Not specified
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
Person responsible: Seddik Hammad
Snapshots: No snapshots
Investigation: Julia/Yan
Assays: Metabolic CCl4
Investigation: Julia/Yan
Study: CCl4 Treatment in mice
Organisms: Mus musculus
SOPs: Sample Collection and Preservation of Blood and...
Data files: Movies for quantification, SAC mice RNA microarray and 1 hidden item
Creators: None
Submitter: Seddik Hammad
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: None
Submitter: Seddik Hammad
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: None
Submitter: Seddik Hammad
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Voids in CCl4
Creators: None
Submitter: Seddik Hammad
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract
Authors: Kamalakannan Radhakrishnan, Yong-Hoon Kim, Yoon Seok Jung, Jina Kim, Don-Kyu Kim, Sung Jin Cho, In-Kyu Lee, Steven Dooley, Chul-Ho Lee, Hueng-Sik Choi
Date Published: 1st Oct 2020
Publication Type: Journal
DOI: 10.3390/ijms21197148
Citation: IJMS 21(19):7148
Abstract
Authors: Fatma El-Zahraa Ammar Mohamed, Seddik Hammad, Tu Vinh Luong, Bedair Dewidar, Rajai Al-Jehani, Nathan Davies, Steven Dooley, Rajiv Jalan
Date Published: 1st Aug 2020
Publication Type: Journal
DOI: 10.1016/j.prp.2020.152980
Citation: Pathology - Research and Practice 216(8):152980
Abstract (Expand)
Authors: F. E. A. Mohamed, S. Hammad, T. V. Luong, B. Dewidar, R. Al-Jehani, N. Davies, S. Dooley, R. Jalan
Date Published: 25th Jul 2020
Publication Type: Journal
PubMed ID: 32703481
Citation: Pathol Res Pract. 2020 Aug;216(8):152980. doi: 10.1016/j.prp.2020.152980. Epub 2020 May 19.
Abstract (Expand)
Authors: M. Han, Z. C. Nwosu, W. Pioronska, M. P. Ebert, S. Dooley, C. Meyer
Date Published: 22nd Feb 2020
Publication Type: Journal
PubMed ID: 32082178
Citation: Front Physiol. 2020 Jan 31;10:1606. doi: 10.3389/fphys.2019.01606. eCollection 2019.
Abstract (Expand)
Authors: M. Han, W. Pioronska, S. Wang, Z. C. Nwosu, C. Sticht, S. Wang, Y. Gao, M. P. Ebert, S. Dooley, C. Meyer
Date Published: 6th Feb 2020
Publication Type: Journal
PubMed ID: 32029710
Citation: Cell Death Dis. 2020 Feb 6;11(2):104. doi: 10.1038/s41419-020-2295-5.