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- Jochen Hampe
SEEK ID: https://seek.lisym.org/people/56
Location:
Germany
Expertise: Not specified
Tools: Not specified
ORCID: Not specified
LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI) (Universitätsklinikum Dresden - Medizinische Klinik I, Bereich Gastroenterologie & Hepatologie)
LiSyM network (Universitätsklinikum Dresden - Medizinische Klinik I, Bereich Gastroenterologie & Hepatologie) ; LiSyM Scientific Leadership Team (LiSyM-LT) (Universitätsklinikum Dresden - Medizinische Klinik I, Bereich Gastroenterologie & Hepatologie) ; LiSyM-Krebs Partnering (Universitätsklinikum Dresden - Medizinische Klinik I, Bereich Gastroenterologie & Hepatologie) ; LiSyM-Krebs (Zentrum für Informationsdienste und Hochleistungsrechnen (ZIH), Technische Universität Dresden)
Related items
LiSyM-Krebs
Programme: LiSyM-Krebs
Public web page: Not specified
Organisms: Homo sapiens
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Programme: LiSyM-Krebs
Public web page: https://www.ptj.de/projektfoerderung/gesundheitsforschung/lisym-krebs
Organisms: Not specified
Day-to-day science within the LiSyM is overseen and directed by the the LiSyM Scientific Leadership Team. This coordination team comprises the pillar coordinators and additional LiSyM members, and ensures smooth interaction between multi-skilled groups, often working in different institutions and across significant distances within Germany.
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/who-we-are
Organisms: Not specified
One of the tasks of the healthy liver is to store fat. Yet, at some stage, too much fat makes the liver sick. One critical time point occurs when a healthy fatty liver becomes inflamed and progresses to steatohepatitis, or NASH.
LiSyM-Pillar I will identify what events lead to this transition. Does it occur in all parts of the liver? Which molecules indicate that it is taking place? Can the degeneration be stopped or undone - and if so, how?
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research/zones-of-the-liver
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
Country: Germany
City: 01307 Dresden
BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Mouse models of NAFLD have been used in studies of pathogenesis and treatment, and have certain features of the human disease. We performed a systematic transcriptome-wide analysis of liver tissues from patients at different stages of NAFLD progression (ranging from healthy obese individuals to those with steatosis), as well as rodent models of NAFLD, to identify
...
Creators: Mario Brosch, Jochen Hampe, Clemens Schafmayer, Witigo von Schönfels
Submitter: Mario Brosch
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Mouse models of NAFLD have been used in studies of pathogenesis and treatment, and have certain features of the human disease. We performed a systematic transcriptome-wide analysis of liver tissues from patients at different stages of NAFLD progression (ranging from healthy obese individuals to those with steatosis), as well as rodent models of NAFLD, to identify
...
Creators: Mario Brosch, Jochen Hampe, Clemens Schafmayer, Witigo von Schönfels
Submitter: Mario Brosch
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: K. Teo, K. W. M. Abeysekera, L. Adams, E. Aigner, Q. M. Anstee, J. M. Banales, R. Banerjee, P. Basu, T. Berg, P. Bhatnagar, S. Buch, A. Canbay, S. Caprio, A. Chatterjee, Y. D. Ida Chen, A. Chowdhury, A. K. Daly, C. Datz, D. de Gracia Hahn, J. K. DiStefano, J. Dong, A. Duret, C. Emdin, M. Fairey, G. S. Gerhard, X. Guo, J. Hampe, M. Hickman, L. Heintz, C. Hudert, H. Hunter, M. Kelly, J. Kozlitina, M. Krawczyk, F. Lammert, C. Langenberg, J. Lavine, L. Li, H. K. Lim, R. Loomba, P. K. Luukkonen, P. E. Melton, T. A. Mori, N. D. Palmer, C. A. Parisinos, S. G. Pillai, F. Qayyum, M. C. Reichert, S. Romeo, J. I. Rotter, Y. R. Im, N. Santoro, C. Schafmayer, E. K. Speliotes, S. Stender, F. Stickel, C. D. Still, P. Strnad, K. D. Taylor, A. Tybjaerg-Hansen, G. R. Umano, M. Utukuri, L. Valenti, L. E. Wagenknecht, N. J. Wareham, R. M. Watanabe, J. Wattacheril, H. Yaghootkar, H. Yki-Jarvinen, K. A. Young, J. P. Mann
Date Published: 31st Aug 2020
Publication Type: Journal
PubMed ID: 32882372
Citation: J Hepatol. 2020 Aug 31. pii: S0168-8278(20)33598-4. doi: 10.1016/j.jhep.2020.08.027.
Abstract (Expand)
Authors: V. R. Thangapandi, O. Knittelfelder, M. Brosch, E. Patsenker, O. Vvedenskaya, S. Buch, S. Hinz, A. Hendricks, M. Nati, A. Herrmann, D. R. Rekhade, T. Berg, M. Matz-Soja, K. Huse, E. Klipp, J. K. Pauling, J. A. Wodke, J. Miranda Ackerman, M. V. Bonin, E. Aigner, C. Datz, W. von Schonfels, S. Nehring, S. Zeissig, C. Rocken, A. Dahl, T. Chavakis, F. Stickel, A. Shevchenko, C. Schafmayer, J. Hampe, P. Subramanian
Date Published: 26th Jun 2020
Publication Type: Journal
PubMed ID: 32591434
Citation: Gut. 2020 Jun 26. pii: gutjnl-2020-320853. doi: 10.1136/gutjnl-2020-320853.
Abstract (Expand)
Authors: H. Innes, S. Buch, S. Hutchinson, I. N. Guha, J. R. Morling, E. Barnes, W. Irving, E. Forrest, V. Pedergnan, D. Goldberg, E. Aspinall, S. Barclay, P. Hayes, J. Dillon, H. D. Nischalke, P. Lutz, U. Spengler, J. Fischer, T. Berg, M. Brosch, F. Eyer, C. Datz, S. Mueller, T. Peccerella, P. Deltenre, A. Marot, M. Soyka, A. McQuillin, M. Y. Morgan, J. Hampe, F. Stickel
Date Published: 16th Jun 2020
Publication Type: Journal
PubMed ID: 32561361
Citation: Gastroenterology. 2020 Jun 16. pii: S0016-5085(20)34767-3. doi: 10.1053/j.gastro.2020.06.014.
Abstract (Expand)
Authors: F. Segovia-Miranda, H. Morales-Navarrete, M. Kucken, V. Moser, S. Seifert, U. Repnik, F. Rost, M. Brosch, A. Hendricks, S. Hinz, C. Rocken, D. Lutjohann, Y. Kalaidzidis, C. Schafmayer, L. Brusch, J. Hampe, M. Zerial
Date Published: 2nd Dec 2019
Publication Type: Not specified
PubMed ID: 31792455
Citation: Nat Med. 2019 Dec 2. pii: 10.1038/s41591-019-0660-7. doi: 10.1038/s41591-019-0660-7.
Abstract (Expand)
Authors: Oleksandr Ostrenko, Jochen Hampe, Lutz Brusch
Date Published: 1st Dec 2019
Publication Type: Not specified
DOI: 10.1038/s41598-019-40853-7
Citation: Sci Rep 9(1) : 823