Web page: https://www.biologie.hu-berlin.de/de/
Institutions: Humboldt-Universität zu Berlin - Institute of Biologyhttps://orcid.org/0000-0002-0567-7075
Tools: Cytometry and fluorescent microscopy, FBA, Dynamic modeling/dMod, Computational and theoretical biology, Partial differential equations, kinetic modelling, live cell imaging, Bifurcation analysis, Mathematical Modelling, qPCR, Algebraic equations
Institutions: Humboldt-Universität zu Berlin - Institute of Biology
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Organisms: Not specified
One of the tasks of the healthy liver is to store fat. Yet, at some stage, too much fat makes the liver sick. One critical time point occurs when a healthy fatty liver becomes inflamed and progresses to steatohepatitis, or NASH.
LiSyM-Pillar I will identify what events lead to this transition. Does it occur in all parts of the liver? Which molecules indicate that it is taking place? Can the degeneration be stopped or undone - and if so, how?
Public web page: http://www.lisym.org/our-work/pillar-research/zones-of-the-liver
Start date: 1st Jan 2016