C-TIP-HCC network

*C-TIP-HCC *- Mechanism-based Multiscale Model to Dissect the Tipping Point from Liver Cirrhosis to Hepatocellular Carcinoma

The ultimate goal of the C-TIP-HCC is a „mechanistic multiscale model to describe dynamic changes in regenerative nodes across a tipping point (TIP) towards development in patients with cirrhosis to facilitate early monitoring and intervention“ and facilitate intervention“. To achieve this, we will conduct in-depth studies on cirrhotic regenerative nodes.

Programme: LiSyM-Krebs - Systemmedizinisches Forschungsnetz zur Früherkennung und Prävention von Leberkrebs

SEEK ID: https://seek.lisym.org/projects/19

Public web page: Not specified

Organisms: Homo sapiens, Mus musculus

FAIRDOM PALs: No PALs for this Project

Project created: 1st Dec 2021

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Johannes Bode

Steven Dooley

Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network, SMART-NAFLD

Institutions: Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University

Stefan Hoehme

Projects: LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, C-TIP-HCC network

Institutions: Universität Leipzig - Institute for Computer Science (Bioinformatics), Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie

Olga Krebs

Projects: LiSyM PALs, LiSyM network, LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM-Krebs Partnering, Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, DEEP-HCC network, C-TIP-HCC network

Institutions: HITS gGmbH

Expertise: big data, Systems Biology, Genetics, wet lab

Tools: SEEK, openBis, Protege, Copasi, JWS online RightFiled

I am a researcher at the Scientific Databases and Visualization Group at Heidelberg Institute for Theoretical Studies (HITS) , one of the developers of SabioRK - System for the Analysis of Biochemical Pathways - Reaction Kinetics (http://sabiork.h-its.org/) . I am working on design and maintenance of the information systems to store, query and analyse systems biology data; definition and implementation of methods for the integration of data from multiple sources. In SySMO-DB project ...

Wolfgang Müller

Projects: LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM PALs, LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network, SMART-NAFLD, DEEP-HCC network

Institutions: HITS gGmbH

I am a trained computer scientist (Habilitation) and physicist (Diploma). My interest is interactive search for information, as well as preparing data for FAIR reuse, a.k.a curation. Within LiSyM I am coordinator of the data management services.

LiSyM-Krebs - Systemmedizinisches Forschungsnetz zur Früherkennung und Prävention von Leberkrebs

LiSyM-Krebs ist ein nationales Forschungsnetz zur Früherkennung und Prävention von Leberkrebs, das unter Verwendung des systemmedizinischen Forschungsansatzes die komplexen, dynamischen Prozesse der Krankheitsprogression analysiert, um ausgehend von den Erkenntnissen aus dem Forschungsnetz LiSyM die Entstehung von Leberkrebs besser zu verstehen, vorherzusagen und im besten Fall sogar zu verhindern. LiSyM-Krebs setzt die erfolgreichen Forschungsaktivitäten der BMBF-Vorgängerprogramme ...

Projects: LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD, DEEP-HCC network, C-TIP-HCC network

Web page: Not specified

HITS gGmbH