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- Johannes Bode
SEEK ID: https://seek.lisym.org/people/35
Location:
Germany
Expertise: Liver injury and regeneration, Inflammation, Jak/STAT pathway, Hepatocytes, Imaging and image analysis, non parenchymal cells
Tools: Immunohistochemistry, Isolation and cultivation of mouse hepatocyte, Isolation purification and separation, Molecular Biology, Mouse surgery, Cell and tissue culture, confocal microscopy
ORCID: Not specified
LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP) (Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie) ; LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF) (Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie) ; LiSyM network (Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie)
LiSyM-Krebs Partnering (Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie) ; LiSyM-Krebs (Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie)
Related items
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Programme: LiSyM-Krebs
Public web page: https://www.ptj.de/projektfoerderung/gesundheitsforschung/lisym-krebs
Organisms: Not specified
LiSyM-Krebs
Programme: LiSyM-Krebs
Public web page: Not specified
Organisms: Homo sapiens
In one in five people with NAFLD, the functioning liver cells, the hepatocytes, are replaced by connective tissue. Eventually this fibrosis becomes irreversible. In this state the liver is like a ‘scar that never heals’. Through it, the liver loses many of its vital functions.
LiSyM-Pillar II wants to know more about which factors promote fibrosis and the conditions under which fibrosis becomes irreversible How can fibrosis be diagnosed as early as possible? Researchers in the pillar are also
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
In chronic diseases, at some point the liver can suddenly stop functioning. This is called acute-on-chronic liver failure, or ACLF. This is the leading cause of death in liver patients and is often provoked by the use of transcription or freely available drugs or alcohol abuse. For this condition we need an effective treatment quickly.
LiSyM-Pillar III researches the factors that contribute significantly to ACLF. What exactly happens then? Are there any early signs that would enable ACLF to be
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Rattus rattus
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
Abstract (Expand)
Authors: C. Ehlting, J. Rex, U. Albrecht, R. Deenen, C. Tiedje, K. Kohrer, O. Sawodny, M. Gaestel, D. Haussinger, J. G. Bode
Date Published: 30th Jul 2019
Publication Type: Not specified
PubMed ID: 31363109
Citation: Sci Rep. 2019 Jul 30;9(1):11021. doi: 10.1038/s41598-019-46791-8.
Abstract (Expand)
Authors: S. Sobotta, A. Raue, X. Huang, J. Vanlier, A. Junger, S. Bohl, U. Albrecht, M. J. Hahnel, S. Wolf, N. S. Mueller, L. A. D'Alessandro, S. Mueller-Bohl, M. E. Boehm, P. Lucarelli, S. Bonefas, G. Damm, D. Seehofer, W. D. Lehmann, S. Rose-John, F. van der Hoeven, N. Gretz, F. J. Theis, C. Ehlting, J. G. Bode, J. Timmer, M. Schilling, U. Klingmuller
Date Published: 9th Oct 2017
Publication Type: Not specified
PubMed ID: 29062282
Citation: Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017.
Abstract (Expand)
Authors: K. Breitkopf-Heinlein, C. Meyer, C. Konig, H. Gaitantzi, A. Addante, M. Thomas, E. Wiercinska, C. Cai, Q. Li, F. Wan, C. Hellerbrand, N. A. Valous, M. Hahnel, C. Ehlting, J. G. Bode, S. Muller-Bohl, U. Klingmuller, J. Altenoder, I. Ilkavets, M. J. Goumans, L. J. Hawinkels, S. J. Lee, M. Wieland, C. Mogler, M. P. Ebert, B. Herrera, H. Augustin, A. Sanchez, S. Dooley, P. Ten Dijke
Date Published: 25th Mar 2017
Publication Type: Not specified
PubMed ID: 28336518
DOI: 10.1136/gutjnl-2016-313314
Citation: Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.
Abstract (Expand)
Authors: K. Breitkopf-Heinlein, C. Meyer, C. Konig, H. Gaitantzi, A. Addante, M. Thomas, E. Wiercinska, C. Cai, Q. Li, F. Wan, C. Hellerbrand, N. A. Valous, M. Hahnel, C. Ehlting, J. G. Bode, S. Muller-Bohl, U. Klingmuller, J. Altenoder, I. Ilkavets, M. J. Goumans, L. J. Hawinkels, S. J. Lee, M. Wieland, C. Mogler, M. P. Ebert, B. Herrera, H. Augustin, A. Sanchez, S. Dooley, P. Ten Dijke
Date Published: 23rd Mar 2017
Publication Type: Not specified
PubMed ID: 28336518
DOI: 10.1136/gutjnl-2016-313314
Citation: Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.
Abstract
Authors: Katharina Beuke, Frank A. Schildberg, Federico Pinna, Ute Albrecht, Roman Liebe, Michaela Bissinger, Peter Schirmacher, Steven Dooley, Johannes G. Bode, Percy A. Knolle, Ursula Kummer, Kai Breuhahn, Sven Sahle
Date Published: 1st Mar 2017
Publication Type: Not specified
DOI: 10.1111/febs.14022
Citation: FEBS J 284(5) : 796