Humboldt-Universität zu Berlin - Institute for Theoretical Biology (ITB)
Web page: https://itb.biologie.hu-berlin.de/
Country: 
Germany
City: 10115 Berlin
Address:
Philippstr. 13, Haus 4
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Former postdoc in the Theoretical Biophysics group headed by Edda Klipp at Humboldt-Universität zu Berlin and member of the LiSyM network, I am now an independent Group Leader at the Technical University of Munich focusing on developing an advanced bioinformatics toolbox for analyzing, integrating, and mining of various omics data in the context of precision medicine as well as molecular disease and patient subtyping.
Interested in modelling metabolism, predicting metabolic phenotypes and dynamic transitions in metabolism. Also using partially and incompletely characterized models (probabilistic predictions).
Projects: LiSyM PALs, Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), Liver Function Diagnostics (LiSyM-LiFuDi - Pillar IV), LiSyM network, LiSyM-Krebs Partnering
Institutions: Humboldt-Universität zu Berlin - Institute for Theoretical Biology (ITB)
https://orcid.org/0000-0003-1725-179X
We are investigating liver metabolism and function with the help of computational models and methods.
Read more about the LiSyM junior group at: www.livermetabolism.com
Junior Group Leader
Dr. Matthias König
Institute for Theoretical Biology
Humboldt-University Berlin
Invalidenstraße 43, 10117 Berlin, Germany
phone +49 30 2093-8450
konigmatt@googlemail.com
The liver is the central metabolic organ of our body playing a crucial role in the clearance of drugs, xenobiotics and numerous metabolites
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This comprises the whole LiSyM network
Public web page: http://www.lisym.org
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. LiSyM-EMI looks into the transition from steatosis to non-alcoholic steatohepatitis (NASH) as the disease-defining moment in NAFLD. A systems analysis of these early disease events will be performed to elucidate the molecular mechanisms that trigger disease establishment.
Public web page: Not specified
This generic project is intended to be a forum for all LiSyM partner and external stakeholders interested in participating in the BMBF initiative LiSyM-Krebs.
Data (breath tests scores, imaging data from MRE, histopathological characterization and proteomics data of liver biopsies) will be acquired from two different groups of patients to be used in computer-assisted diagnostic tools for early detection and comprehensive evaluation of altered liver functions.
Public web page: Not specified
This is a generic project that comprises all LiSyM data management PALs and associated FAIRDOM PALs, as well as the LiSyM data management team.
Public web page: Not specified
