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- Tilo Wuensch
SEEK ID: https://seek.lisym.org/people/43
Location:
Germany
Expertise: Not specified
Tools: Not specified
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Disorders of the liver show up through changes in blood tests. These blood tests indicate markers for events taking place in the liver. Usually studies of liver tissue cannot be performed: as liver samples would need to be obtained through a liver biopsy, and this procedure is not without risk, therefore these samples are usually unavailable. Complex metabolism models based on existing and new scientific data can simulate changes in the liver caused by disease. They often reveal unknown relationships
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Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research/the-liver-is-very-patient
Start date: 1st Jan 2016
Organisms: Homo sapiens
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
The data file contains basal information About the enroled study subjects. Further Details are provided upon request to tilo.wuensch@charite.de
Creators: None
Submitter: Tilo Wuensch
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: N. Berndt, J. Eckstein, N. Heucke, T. Wuensch, R. Gajowski, M. Stockmann, D. Meierhofer, H. G. Holzhutter
Date Published: 8th Oct 2020
Publication Type: Journal
PubMed ID: 33030799
Citation: FEBS J. 2020 Oct 8. doi: 10.1111/febs.15587.
Abstract (Expand)
Authors: H. G. Holzhutter, T. Wuensch, R. Gajowski, N. Berndt, S. Bulik, D. Meierhofer, M. Stockmann
Date Published: 6th Feb 2020
Publication Type: Not specified
PubMed ID: 32020249
Citation: Arch Toxicol. 2020 Feb;94(2):401-415. doi: 10.1007/s00204-020-02654-0. Epub 2020 Feb 4.
Abstract (Expand)
Authors: T. Wuensch, J. Wizenty, J. Quint, W. Spitz, M. Bosma, O. Becker, A. Adler, W. Veltzke-Schlieker, M. Stockmann, S. Weiss, M. Biebl, J. Pratschke, F. Aigner
Date Published: 17th May 2019
Publication Type: Not specified
PubMed ID: 31093274
Citation: Gastroenterol Res Pract. 2019 Apr 9;2019:3784172. doi: 10.1155/2019/3784172. eCollection 2019.
Abstract (Expand)
Authors: T. Wuensch, J. Quint, V. Mueller, A. Mueller, J. Wizenty, M. Kaffarnik, B. Kern, M. Stockmann, M. Biebl, J. Pratschke, F. Aigner
Date Published: 25th Mar 2019
Publication Type: Not specified
PubMed ID: 30904213
Citation: Clin Nutr ESPEN. 2019 Apr;30:131-137. doi: 10.1016/j.clnesp.2019.01.004. Epub 2019 Jan 31.
Abstract (Expand)
Authors: T. Wuensch, N. Heucke, J. Wizenty, J. Quint, B. Sinn, R. Arsenic, M. Jara, M. Kaffarnik, J. Pratschke, M. Stockmann
Date Published: 14th Mar 2019
Publication Type: Not specified
PubMed ID: 30869529
Citation: Am J Physiol Gastrointest Liver Physiol. 2019 Mar 14. doi: 10.1152/ajpgi.00335.2018.
Improving liver funcion diagnostics by developing computitional models based on patients' data (liver function, liver stiffness, clinical data, proteomics, specific enzyme activities) and translation of modeling results in clinical practice
Creator: Tilo Wuensch
Submitter: Tilo Wuensch
Pillar IV Jamboree
• (10 min) Introduction to Pillar IV (Hergo Holzhütter)
• (20 min) Precise Measurement of Hepatic Elasticity for Fibrosis Detection (Christian Hudert)
• (20 min) Tissue Scale Metabolic Modelling (Sascha Bulik)
• (10 min) Multi-scale models for liver function tests (Matthias König)
• (20 min) Improving the diagnostic precision of the 13C-methacetin dynamic liver function test
(LiMAx) (Tilo Wünsch)
• (20 min) Mathematical Modelling of Improved Liver Function Breath Test (Hergo
...
Creator: Tilo Wuensch
Submitter: Matthias König