Jan Grzegorzewski
SEEK ID: http://localhost:3000/people/117
Location:
Germany
ORCID: Not specified
Joined: 1st Dec 2018
Expertise: Not specified
Tools: Not specified
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This comprises the whole LiSyM network
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Dr. Matthias König (Humboldt University, Berlin) models the human liver on the computer. His simulations show the extent of individual differences in liver function and the external factors influencing it. König has shown that smoking falsifies the result of an important liver test (LiMAx). With his models, drug doses can be calculated so that they can be administered in doses that do not harm the liver.
Public web page: https://livermetabolism.com
Start date: 1st Jan 2016
A multitude of pharmacokinetics studies have been published. However, due to the lack of an open database, pharmacokinetics data, as well as the corresponding meta-information, have been difficult to access. We present PK-DB (https://develop.pk-db.com), an open database for pharmacokinetics information from clinical trials including pre-clinical research. PK-DB provides curated information on (i) characteristics of studied patient cohorts and subjects (e.g. age, bodyweight, smoking status); (ii) ...
Submitter: Matthias König
Investigation: Stratification and Personalization of Computati...
Assays: No Assays
Abstract (Expand)
Authors: J. Grzegorzewski, J. Brandhorst, K. Green, D. Eleftheriadou, Y. Duport, F. Barthorscht, A. Koller, D. Y. J. Ke, S. De Angelis, M. Konig
Date Published: 5th Nov 2020
Publication Type: Journal
Abstract (Expand)
Authors: Matthias König, Jan Grzegorzewski
Date Published: 1st Jun 2020
Publication Type: Misc
Abstract (Expand)
Authors: Jan Grzegorzewski, Janosch Brandhorst, Dimitra Eleftheriadou, Kathleen Green, Matthias König
Date Published: 9th Sep 2019
Publication Type: Unpublished
PK-DB: PharmacoKinetics DataBase for Individualized and Stratified Computational Modeling Jan Grzegorzewski, Janosch Brandhorst, Dimitra Eleftheriadou, Kathleen Green, Matthias König bioRxiv 760884; doi: https://doi.org/10.1101/760884
Creators: Matthias König, Jan Grzegorzewski
Submitter: Matthias König
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