In vivo and in vitro characterization of primary human macrophages and their inflammatory state

In this study, we investigated human LMs in tissue sections as well as isolated from human liver tissues which were characterized both in suspension and in adherent cultures to find out whether the inflammatory state of primary human LMs corresponds to patients and disease characteristics and whather it is possible to maintain the macrophage pattern in suspension as well as in adherent cultures with just a few limitations. (CCA: cholangiocarcinoma, CRLM: colorectal liver metastasis, FNH: focal nodular hyperplasia; HCC: hepatocellular carcinoma, LMs: liver macrophages, MDMs: monocyte-derived macrophages, NPCs: non-parenchymal cells,

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Created: 12th Apr 2021 at 14:51

Last updated: 11th May 2021 at 14:26

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