Presentations

Talk at the Jamboree 2021 about epigenomic map of human liver zonation and loss of zonation in end-stage liver disease

Jamboree presentation

Workshop from LiSyM retreat in January 2020. Additional slides devoted to Social Media for Academics. Developed by Peter Krinenberg from https://naturalscience.careers/

We face a reproducibility crisis and computational science, with most published models neither being accessible nor reproducible. The Systems Biology Markup Language (SBML) is the de facto standard format for encoding pathway based models, which provides a means for exchanging process based models between researchers and tools. The talk gives an overview of SBML and SBML-based tools.

Orally presented in Hünfeld Retreat, 2018.

The spatial separation of metabolic functions along the porto-central axis within the liver lobule is termed liver zonation. The zonated metabolic endowment of hepatocytes along the sinusoid are partially influenced by adaption to changing contents of nutrients and oxygen, but is mainly regulated by the morphogenic Wnt/β-Catenin signaling pathway. How morphogens contribute to the lobular distribution of metabolic pathways is part of an evolving field in science since the last decade. For long, ...