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Fig. S1 Liver cell proliferation, resident macrophage and leucocyte numbers upon Galunisertib treatment in 26-weeks-old Abcb4ko mice. a) Representative images of Ki-67 (proliferation marker), F4/80 (resident macrophages) and CD45 (leukocyte common marker) positive signals in liver tissues upon Galunisertib or vehicle administration. Scale bars are 100 µm. b and c) show numbers of proliferating hepatocytes and non-parenchymal cells, as indicated by Ki-67 positivity. d and e) quantification of F4/80 positive areas and number of CD45 positive cells, among different groups. Data are means ± SD of 5–7 mice per group. N.S.: P > 0.05; **: P < 0.01 compared with untreated livers unless otherwise indicated. (PPTX 4035 KB)

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Created: 13th Dec 2021 at 09:27

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Version 1 (earliest) Created 13th Dec 2021 at 09:27 by Seddik Hammad

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