To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure.

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Abstract:

Variceal bleeding is a consequence of severe portal hypertension in patients with liver cirrhosis. Although the rate of bleeding has decreased over time, variceal bleeding in the presence of acute-on-chronic liver failure (ACLF) carries a high risk of treatment failure and short-term mortality. Treatment and/or removal of precipitating events (mainly bacterial infection and alcoholic hepatitis) and decrease of portal pressure may improve outcome of patients with acute decompensation or ACLF. Transjugular intrahepatic portosystemic shunts (TIPSs), especially in the preemptive situation, have been found to efficiently control bleeding, prevent rebleeding, and reduce short-term mortality. Therefore, TIPS placement should be considered as an option in the management of ACLF patients with variceal bleeding.

SEEK ID: https://seek.lisym.org/publications/366

PubMed ID: 37286178

Projects: DEEP-HCC network, Forschungsnetzwerk LiSyM-Krebs

Publication type: Journal

Journal: Semin Liver Dis

Citation: Semin Liver Dis. 2023 May;43(2):189-205. doi: 10.1055/a-2107-0576. Epub 2023 Jun 7.

Date Published: 17th Jul 2023

Registered Mode: by PubMed ID

Authors: W. Gu, M. Kimmann, W. Laleman, M. Praktiknjo, J. Trebicka

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