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Primary hepatocytes from a preclinical mouse model fed with high-sugar and high-fat diet are used to develop a data-based mathematical model that identifies the basal phosphorylation rate of the tyrosine kinase receptor MET as the main dysregulated parameter driving fatty liver disease.
Creators: Sebastian Burbano De Lara, Ursula Klingmüller
Submitter: Olga Krebs
Raw data of RNA-seq analysis of primary murine hepatocytes treated with Hh modulating compounds
Creators: None
Submitter: Fritzi Ott