Presentations

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16 Presentations visible to you, out of a total of 17

The spatial separation of metabolic functions along the porto-central axis within the liver lobule is termed liver zonation. The zonated metabolic endowment of hepatocytes along the sinusoid are partially influenced by adaption to changing contents of nutrients and oxygen, but is mainly regulated by the morphogenic Wnt/β-Catenin signaling pathway. How morphogens contribute to the lobular distribution of metabolic pathways is part of an evolving field in science since the last decade. For long, ...

Creator: Erik Kolbe

Submitter: Erik Kolbe

I gave this talk at the SBMC 2018 in Bremen (Session: Systems Medicine & Clinical applications)

Creator: Christian Holland

Submitter: Christian Holland

Improved evaluation of caffeine-based dynamical liver function tests by accounting for lifestyle and pharmacological modifiers like smoking and oral contraceptive use

Matthias König1,*, Ute Hofmann2, Jan Grzegorzewski1, Reinhold Kerb2, Svitlana Igel2, Elke Schäffeler2 and Matthias Schwab2,3

1Institute for Theoretical Biology, Institute of Biology, Humboldt University, Berlin, Germany, koenigmx@hu-berlin.de, orcid.org/0000-0003-1725-179X 2Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, ...

Creator: Matthias König

Submitter: Matthias König

In the growing elderly societies, the incidence of primary and secondary liver tumors is continuously increasing. Surgical interventions like partial liver resections are often the only curative therapy removing more than 70% of the total liver mass. In humans, 20% to 30% of the remaining liver is required for liver regeneration. Successful restoration of the liver mass ultimately depends on the regenerative and metabolic capacity of the hepatocytes in the remnant liver. This, however, might be ...

Creators: Matthias König, Bruno Christ

Submitter: Matthias König

No description specified

Creator: Seddik Hammad

Submitter: Seddik Hammad

No description specified

Creator: Seddik Hammad

Submitter: Seddik Hammad

No description specified

Creator: Seddik Hammad

Submitter: Seddik Hammad

No description specified

Creator: Seddik Hammad

Submitter: Seddik Hammad

No description specified

Creator: Seddik Hammad

Submitter: Seddik Hammad

Poster presentation at SBMC 2018 (Bremen)

Creators: Martin Golebiewski, Olga Krebs, Hadas Leonov, Wolfgang Müller, Stuart Owen, Maja Rey, Natalie Stanford, Andreas Weidemann, Ulrike Wittig, Katy Wolstencroft, Jacky L. Snoep, Carole Goble

Submitter: Martin Golebiewski

LiSyM/de.NBI/ERASysAPP Tutorial: How to Share FAIR — The FAIRDOM Data and Model Management Practice Introduction into SABIO-RK

Creator: Maja Rey

Submitter: Martin Golebiewski

LiSyM/de.NBI/ERASysAPP Tutorial: How to Share FAIR — The FAIRDOM Data and Model Management Practice Hands-on tasks

Creator: Maja Rey

Submitter: Martin Golebiewski

LiSyM/de.NBI/ERASysAPP Tutorial: How to Share FAIR — The FAIRDOM Data and Model Management Practice Hands-on slides

Creator: Maja Rey

Submitter: Martin Golebiewski

LiSyM/de.NBI/ERASysAPP Tutorial: How to Share FAIR — The FAIRDOM Data and Model Management Practice Introduction slides

Creator: Martin Golebiewski

Submitter: Martin Golebiewski

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