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The Hedgehog Signalling Pathway (LiSyM-JGMMS)10
LiSyM PALs2
LiSyM network2
LiSyM Core Infrastructure and Management (LiSyM-PD)1
LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI)1
LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP)1
LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF)1
LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi)1
Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP)1
Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM)1
Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)1
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LiSyM: Liver Systems Medicine 10
10
Presentations visible to you, out of a total of 18
The spatial separation of metabolic functions along the porto-central axis within the liver lobule is termed liver zonation. The zonated metabolic endowment of hepatocytes along the sinusoid are partially influenced by adaption to changing contents of nutrients and oxygen, but is mainly regulated by the morphogenic Wnt/β-Catenin signaling pathway. How morphogens contribute to the lobular distribution of metabolic pathways is part of an evolving field in science since the last decade. For long, ...
Creator: Erik Kolbe
Submitter: Erik Kolbe