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Programme
LiSyM: Liver Systems Medicine 2
LiSyM-Krebs - Systemmedizinisches Forschungsnetz zur Früherkennung und Prävention von Leberkrebs2
Project
Forschungsnetzwerk LiSyM-Krebs2
SMART-NAFLD2
DEEP-HCC network2
The Hedgehog Signalling Pathway (LiSyM-JGMMS)1
LiSyM network1
LiSyM-Krebs Partnering1
C-TIP-HCC network1
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Institution
German Cancer Research Center (DKFZ), Division of Systems Biology of Signal Transduction1
HITS gGmbH1
Universität Leipzig - Sächsischer Inkubator für Klinische Translation (SIKT)1
Location
Germany2
Expertise
Primary human hepatocytes2
Systems Biology9
Molecular Biology8
Mathematical Modelling6
computational biology5
Biophysics5
Biochemistry4
Genetics4
Bioinformatics4
Data Management4
wet lab4
computational modelling4
liver metabolism4
Imaging and image analysis4
Databases3
Standards3
Hepatocytes3
Signal transduction3
Spatio-temporal Modelling3
Microbiology2
Proteomics2
Liver injury and regeneration2
Liver zonation2
kinetic modelling2
Hedgehog pathway2
functional imaging2
pharmacokinetics2
Lipidomics2
Data-driven ODE modeling2
Data Analysis2
Epigenetics2
Software Engineering1
Python1
Modelling1
Metabolism1
big data1
metabolic networks1
Inflammation1
Jak/STAT pathway1
Wnt signalling pathway1
in vivo imaging1
Animal experimentalist1
Omics1
non parenchymal cells1
Multi-scale Modelling1
Disease modelling1
Nonlinear Dynamics1
Models of Metabolism1
Network Reconstruction1
Modelling Growth Phenotypes1
Probabilistic Models1
Coarse-grained Models of Metabolism1
Organ-On-Chip1
liver models1
Steatosis1
NPCs1
Digital Pathology1
Systems Medicine1
Html1
Data Curation1
Computational Modeling1
Multi-Scale Modeling1
Nextcloud1
Cell cultivation1
Information Retrieval1
Biocuration1
FAIRDOM SEEK1
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Program management team LiSyM-Cancer (project and communications manager)
Former PhD student in LiSyM, at DKFZ Heidelberg in the group of Ursula Klingmüller
(née Schmitt)
The clinical department of Prof. Dr. med Daniel Seehofer performs more than 200 surgical interventions on the liver annually. Therefore, the group has access to a broad variety of liver tissues as well as corresponding patient, clinical laboratory and characterization data. I lead the experimental work group which has a longstandind expertise in the isolation, characterization and application of primary human liver and hepatoma cells. These cells as well as data generated from established liver ...