Presentations
What is a Presentation?Filters
Query
Created At
Updated At
Project
LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP)13
LiSyM network10
LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF)4
Programme
LiSyM: Liver Systems Medicine 24
24
Presentations visible to you, out of a total of 39
Poster presented at Hünfeld Retreat 2018
Creators: André Homeyer, Seddik Hammad, Lars Ole Schwen, Steven Dooley, Andrea Schenk, Uta Dahmen, Henning Höfener, Yan Gao
Submitter: Lars Ole Schwen
Download
The transforming growth factor (TGF)-β has been identified as a master regulator of liver fibrogenesis. Thus, targeting TGF-β1 pathway might modulate chronic liver disease (CLD) development and/or progression in murine model. Galunisertib (Ly2157299), already in clinical studies phase II, is an oral small molecule targeting TGF-β type I receptor (ALK-5).
Creators: Seddik Hammad, Julia Werle
Submitter: Seddik Hammad
