Investigations
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Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)4
LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI)2
LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP)2
LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi)2
LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF)1
The Hedgehog Signalling Pathway (LiSyM-JGMMS)1
LiSyM network1
Forschungsnetzwerk LiSyM-Krebs1
SMART-NAFLD1
DEEP-HCC network1
C-TIP-HCC network1
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13
Investigations visible to you, out of a total of 28
Upon stimulation of cells with transforming growth factorb(TGF-b),Smad proteins form trimeric complexes and activate a broad spectrum of target genes. It remains unresolved which of the possible Smad complexes are formed in cellular contexts and how these contribute to gene expression. Combining quantitative mass spectrometry with a computational selection strategy, we investigate Smad complexes in the mouse hepatoma cell line Hepa1-6.
Submitter: Olga Krebs
Studies: Study about Smad complexes in liver-derived cells
Assays: Modelling asssay II Lucarelli paper, exp assay I Lucarelli paper
