Selected:
The Hedgehog Signalling Pathway (LiSyM-JGMMS) (Project)
Description: Dr. Madlen Matz-Soja (University of Leipzig) investigates the importance of a control mechanism - the hedgehog...
SEEK ID: https://seek.lisym.org/projects/9
Description: Dr. Madlen Matz-Soja (University of Leipzig) investigates the importance of a control mechanism - the hedgehog...
SEEK ID: https://seek.lisym.org/projects/9
- LiSyM: Liver Systems Medicine
- LiSyM Core Infrastructure and Management (LiSyM-PD)
- LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI)
- LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP)
- LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF)
- LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi)
- Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP)
- Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM)
- The Hedgehog Signalling Pathway (LiSyM-JGMMS)
- Role of liver macrophages in different liver pathologies
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_Table S1
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_ Table S3
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_ Table S7
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_ Table S4
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_ Table S4
- Functional consequences of metabolic zonation in murine livers: New insights for an old story_ Table S5
- Functional consequences of metabolic zonation in murine livers: New insights for an old story.
- PALs Meeting Hünfeld 2017 Agenda
- transcript profiling Tick Tock Hedgehog
- Berndt et al. LQF intensities
- Metabolom data cell reports
- Metabolom data cell reports
- Proteomic raw data SAC female mice
- Proteomic raw date SAC male mice
- Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility
- Computational modelling of Hedgehog signalling in liver regeneration
- Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.
- Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
- The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism – A Systems Biology Analysis Using Self-Organizing Maps
- Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis.
- beta-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.
- Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
- Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer.
- Presentation LiSyM Data Management -
1st LiSyM Jamboree & SAB Meeting, Dresden, May 16-17, 2017
Wolfgang Müller and Martin Golebiewski
- LiSyM Junior Group: The Hedgehog Signalling in liver Zonation – Part I
- Poster Erik Schröder LiSyM Jamboree 2017 - Morphogenic impact on liver zonation and metabolism
- Connection of Hedgehog signaling and hepatic steroidogenesis, androgenization and infertility
- The emerging field of morphogens in the adult liver of mice and human – a deep insight into distribution, interaction and regulation
- Poster 35: LiSyM Midterm Evaluation 2018 Madlen Matz-Soja Junior-Group (Leipzig)
- LiSyM Junior Group: The Hedgehog Signalling in Liver Zonation
- Along the porto-central axis – Zone specific isolation of primary hepatocyte and its integration into a metabolic model
- Wnt/β-Catenin and Hh signaling in the adult liver – an insight into distribution, interaction and regulation
- 2nd LiSyM PostDoc and PhD student retreat
- 3rd Disease Maps Community Meeting (DMCM2018)
- 4th International Symposium on Systems Biology of Microbial Infection
- 63rd Annual Conference of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS)
- 7th Conference on Systems Biology of Mammalian Cells (SBMC 2018)
- Basic EASL School: Metabolism, immunity and liver disease
- Hedgehog around the clock
- Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)
- LiSyM PALs
- Project Management PTJ
- LiSyM network
- LiSyM Scientific Leadership Team (LiSyM-LT)
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