Projects: LiSyM network, LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), SMART-NAFLD, Forschungsnetzwerk LiSyM-Krebs, DEEP-HCC network, C-TIP-HCC network
Institutions: German Cancer Research Center (DKFZ), Division of Systems Biology of Signal Transduction, HITS gGmbH
Program management team LiSyM-Cancer (project and communications manager)
Former PhD student in LiSyM, at DKFZ Heidelberg in the group of Ursula Klingmüller
(née Schmitt)
Projects: SMART-NAFLD, Forschungsnetzwerk LiSyM-Krebs
Institutions: German Cancer Research Center (DKFZ), Division of Tumour Metabolism and Microenvironment
https://orcid.org/0000-0002-3924-5756Expertise: liver metabolism, Lipidomics, wet lab
Tools: Cell and tissue culture, Metabolomics, Molecular Biology, qPCR, RNA analysis
Projects: The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM network, Forschungsnetzwerk LiSyM-Krebs, SMART-NAFLD
Institutions: Universität Leipzig - Medizinische Fakultät - Institut für Biochemie, Universitätsklinikum Leipzig - Klinik und Poliklinik für Gastroenterologie, Sektion Hepatologie
https://orcid.org/0000-0001-7225-4809Expertise: Hedgehog pathway
Tools: Cell and tissue culture, confocal microscopy, Immunohistochemistry, qPCR
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM-Krebs Partnering, Forschungsnetzwerk LiSyM-Krebs, C-TIP-HCC network
Institutions: Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie
Expertise: Liver injury and regeneration, Inflammation, Jak/STAT pathway, Hepatocytes, Imaging and image analysis, non parenchymal cells
Tools: Immunohistochemistry, Isolation and cultivation of mouse hepatocyte, Isolation purification and separation, Molecular Biology, Mouse surgery, Cell and tissue culture, confocal microscopy
Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network
Institutions: Universitätsklinikum Düsseldorf - Klinik für Gastroenterologie, Hepatologie und Infektiologie
https://orcid.org/0000-0003-0103-1856Expertise: Biochemistry, Hepatocytes, Inflammation, Liver injury and regeneration, MAP kinases, Macrophages, Jak/STAT pathway, RNA stability, Molecular Biology, wet lab, non parenchymal cells
Tools: Milliplex analysis, qPCR, Molecular Biology, Laser scan microscopy, Immunohistochemistry, Cell and tissue culture, confocal microscopy, Mouse surgery, RNA analysis, rtPCR, Cytometry and fluorescent microscopy, Mouse experiments in vivo, Isolation of primary cells (hepatocytes and non-parenchymal cells)
I received my diploma in biology in 2001 from the Heinrich-Heine-University in Duesseldorf and the Dr. rer. nat. (Ph.D.) degree in 2006 from the University of Hohenheim in Germany. The practical part of my Ph.D. thesis had been realized at the clinic for gastroenterology, hepatology and infectiology at the university hospital in Duesseldorf. After my Ph.D. I focussed my studies on MAP-kinase-regulated cytokine/chemokine expression in response to bacterial or viral pathogens with a main issue on ...
Projects: The Hedgehog Signalling Pathway (LiSyM-JGMMS), LiSyM PALs, LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT), LiSyM-Krebs Partnering, SMART-NAFLD, DEEP-HCC network, Forschungsnetzwerk LiSyM-Krebs
Institutions: Universität Leipzig - Medizinische Fakultät - Institut für Biochemie, Universität Leipzig - Sächsischer Inkubator für Klinische Translation (SIKT)
Group leader of the junior group: The Hedgehog Signalling Pathway (LiSyM-JGMMS)