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Created: 21st Nov 2017 at 14:58
Last updated: 9th Feb 2018 at 12:26
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Projects: LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM network, LiSyM PALs, LiSyM-Krebs Partnering
Institutions: Molecular Hepatology - Dept of Medicine II - Medical Faculty Mannheim - Heidelberg University
Roles: Postdoc
Expertise: Animal experimentalist, Imaging and image analysis, Omics
Tools: Animal facility, Microarray analysis, confocal microscopy, Metabolomics
In one in five people with NAFLD, the functioning liver cells, the hepatocytes, are replaced by connective tissue. Eventually this fibrosis becomes irreversible. In this state the liver is like a ‘scar that never heals’. Through it, the liver loses many of its vital functions.
LiSyM-Pillar II wants to know more about which factors promote fibrosis and the conditions under which fibrosis becomes irreversible How can fibrosis be diagnosed as early as possible? Researchers in the pillar are also
...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
Investigation: Julia/Yan
Study: CCl4 Treatment in mice
Organisms: Mus musculus
SOPs: Sample Collection and Preservation of Blood and...
Data files: Movies for quantification, SAC mice RNA microarray and 1 hidden item
RNA microarray made with primary hepatocytes from female mice with hepatocyte-specific, embryonic knockout of Smoothened
Creator: Christiane Rennert
Submitter: Christiane Rennert
This SOP - Standard Operating Procedure for Sample Collection and Preservation of Blood and
Endometrial Tissue were developed at NIH University of California San Francisco Human Endometrial Tissue and DNA Bank
by Elizabeth Sheldonand, Ramsey A McIntire
Creators: Olga Krebs, Martin Golebiewski, Elizabeth Sheldonand, Ramsey A McIntire
Submitter: Olga Krebs
Investigations: Julia/Yan and 1 hidden item
Studies: CCl4 Treatment in mice and 1 hidden item
Assays: Metabolic CCl4 and 1 hidden item