CCl4 Treatment in mice

Chronic liver diseases (CLD) progression leads to cirrhosis, often cancer, and ultimately to organ failure and death. Because of the complexity of this scenario, a Systems Medicine approach is chosen to develop strategies to better characterize progression and resolution of fibrosis. Pillar II aims to define key molecular mechanisms and structural changes in tissue architecture during the progression of CLD by visualizing and quantifying at a cellular level, tissue and organ scale.

Pillar II dooley

RNA microarray made with primary hepatocytes from female mice with hepatocyte-specific, embryonic knockout of Smoothened

This SOP - Standard Operating Procedure for Sample Collection and Preservation of Blood and
Endometrial Tissue were developed at NIH University of California San Francisco Human Endometrial Tissue and DNA Bank
by Elizabeth Sheldonand, Ramsey A McIntire