Full-Field-of-View Time-Harmonic Elastography of the Native Kidney.

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Abstract:

The purpose of this study was to analyze full-field-of-view maps of renal shear wave speed (SWS) measured by time-harmonic elastography (THE) in healthy volunteers in terms of reproducibility, regional variation and physiologic effects. The kidneys of 37 healthy volunteers were investigated by multifrequency THE. The complete renal parenchyma, as well as cortex and medulla, was analyzed. A subgroup was investigated to test reproducibility (n = 3). Significant differences between SWS in cortex, medulla and full parenchyma were observed (2.10 +/- 0.17, 1.35 +/- 0.11 and 1.71 +/- 0.16 m/s, all p values < 0.001) with mean intra-volunteer standard deviations of repeated measurements of 0.04 m/s (1.6%), 0.06 m/s (4.0%) and 0.08 m/s (4.5%), respectively. No effects of kidney anatomy, age, body mass index, blood pressure and heart rate on SWS were observed. THE allows generation of full-field-of-view SWS maps of native kidneys with high reproducibility.

SEEK ID: https://seek.lisym.org/publications/186

PubMed ID: 29478787

Projects: LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi)

Publication type: Not specified

Journal: Ultrasound Med Biol

Citation: Ultrasound Med Biol. 2018 May;44(5):949-954. doi: 10.1016/j.ultrasmedbio.2018.01.007. Epub 2018 Feb 22.

Date Published: 27th Feb 2018

Registered Mode: Not specified

Authors: S. R. Marticorena Garcia, M. Grossmann, S. T. Lang, M. Nguyen Trong, M. Schultz, J. Guo, B. Hamm, J. Braun, I. Sack, H. Tzschatzsch

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