Assays

Experimental assay Human-NAFLD/eNASH Samples for the eNASH category were obtained in patients undergoing bariatric surgery with a BMI > 30 and subgroups defined by liver histology as follows: eNASH samples were characterized by >5% fat, an inflammation grade of at least 1, fibrosis ≤1 and ballooning ≤1.

Image data for this assay available via link to file folder containing image data for listed patient IDs (patientID in a file name) ...

Experimental assay Human-NAFLD/STEA 8 biopsies from steatosis patients. Samples for the STEA category were obtained in patients undergoing bariatric surgery with a BMI > 30 and subgroups defined by liver histology as follows: STEA samples had >5% fat, no inflammation, fibrosis ≤1 and ballooning ≤1.

Image data for this assay available via link to file folder containing image data for listed patient IDs (patientID in a file name)

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Experimental assay Human-NAFLD/NC 6 biopsies from normal control patients. : NC samples showed steatosis ≤5%, no inflammation, no ballooning and no fibrosis and were obtained during liver resections or biopsy in non-hepatobiliary malignancy in patients with a BMI<30kg/m2. Livers were either free of metastases or a distance of at least 2 cm to the next metastasis observed.

Image data for this assay available via link to file folder containing ...

Experimental assay Human-NAFLD/HO , 4 biopsies from healthy obese patients. Samples for the HO category were obtained in patients undergoing bariatric surgery with a BMI > 30 and subgroups defined by liver histology as follows: HO samples showed a normal liver histology such as the NC samples.

-h692a -h6758 -h6922 -h7230

All file here

Files can be opened and visualised with http://motiontracking.mpi-cbg.de/get/ software

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: periportal (PP)

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: intermediate (IZ)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; hepatic zone: intermediate (IZ)

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: pericentral (CV)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; hepatic zone: pericentral (CV)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; periportal (PP)