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- Fabian Rost
SEEK ID: https://seek.lisym.org/people/29
Location:
Germany
Expertise: Biophysics, Spatio-temporal Modelling, Mathematical Modelling
Tools: Mathematical Modelling, Multiscale simulation, Stability analysis
Related items
One of the tasks of the healthy liver is to store fat. Yet, at some stage, too much fat makes the liver sick. One critical time point occurs when a healthy fatty liver becomes inflamed and progresses to steatohepatitis, or NASH.
LiSyM-Pillar I will identify what events lead to this transition. Does it occur in all parts of the liver? Which molecules indicate that it is taking place? Can the degeneration be stopped or undone - and if so, how?
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research/zones-of-the-liver
Start date: 1st Jan 2016
Organisms: Mus musculus, Rattus rattus, Rattus norvegicus, Homo sapiens
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
Abstract (Expand)
Authors: Paula Heinke, Fabian Rost, Julian Rode, Thilo Welsch, Kanar Alkass, Joshua Feddema, Mehran Salehpour, Göran Possnert, Henrik Druid, Lutz Brusch, Olaf Bergmann
Date Published: 7th Aug 2020
Publication Type: Unpublished
DOI: 10.1101/2020.08.07.230086
Citation: biorxiv;2020.08.07.230086v1,[Preprint]
Abstract (Expand)
Authors: F. Segovia-Miranda, H. Morales-Navarrete, M. Kucken, V. Moser, S. Seifert, U. Repnik, F. Rost, M. Brosch, A. Hendricks, S. Hinz, C. Rocken, D. Lutjohann, Y. Kalaidzidis, C. Schafmayer, L. Brusch, J. Hampe, M. Zerial
Date Published: 2nd Dec 2019
Publication Type: Not specified
PubMed ID: 31792455
Citation: Nat Med. 2019 Dec 2. pii: 10.1038/s41591-019-0660-7. doi: 10.1038/s41591-019-0660-7.