SEEK ID: https://seek.lisym.org/people/23
Location: Germany
ORCID: Not specified
Joined: 2nd May 2017
Expertise: Not specified
Tools: Not specified
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Liver Systems Medicine : striving to develop non-invasive methods for diagnosing and treating NAFLD by combining mathematical modeling and biological research. LiSyM, is a multidisciplinary research network, in which molecular and cell biologists, clinical researchers, pharmacologists and experts in mathematical modeling examine the liver in its entirety. LiSyM research focuses on the metabolic liver disease non-alcoholic fatty liver disease (NAFLD), which includes non-alcoholic steatohepatitis ...
Projects: LiSyM Core Infrastructure and Management (LiSyM-PD), LiSyM Pillar I: Early Metabolic Injury (LiSyM-EMI), LiSyM Pillar II: Chronic Liver Disease Progression (LiSyM-DP), LiSyM Pillar III: Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF), LiSyM Pillar IV: Liver Function Diagnostics (LiSyM-LiFuDi), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), LiSyM PALs, Project Management PTJ, LiSyM network, LiSyM Scientific Leadership Team (LiSyM-LT)
Web page: https://www.lisym.org/
In chronic diseases, at some point the liver can suddenly stop functioning. This is called acute-on-chronic liver failure, or ACLF. This is the leading cause of death in liver patients and is often provoked by the use of transcription or freely available drugs or alcohol abuse. For this condition we need an effective treatment quickly. LiSyM-Pillar III researches the factors that contribute significantly to ACLF. What exactly happens then? Are there any early signs that would enable ACLF to be ...
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org/our-work/pillar-research
Start date: 1st Jan 2016
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Rattus rattus
This comprises the whole LiSyM network
Programme: LiSyM: Liver Systems Medicine
Public web page: http://www.lisym.org
Start date: 1st Jan 2016
Organisms: Rattus norvegicus, Rattus rattus, Mus musculus, Homo sapiens
Country: Germany
City: 66421 Homburg/Saar
Abstract
Authors: Ersin Karatayli, Rabea A. Hall, Susanne N. Weber, Steven Dooley, Frank Lammert
Date Published: 1st Feb 2019
Publication Type: Not specified
DOI: 10.1016/j.bbadis.2018.11.008
Citation: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865(2) : 298
Abstract (Expand)
Authors: M. Jamka, A. Arslanow, A. Bohner, M. Krawczyk, S. N. Weber, F. Grunhage, F. Lammert, C. S. Stokes
Date Published: 8th Mar 2018
Publication Type: Not specified
PubMed ID: 29514138
DOI: 10.1159/000485180
Citation: Digestion. 2018;97(4):298-308. doi: 10.1159/000485180. Epub 2018 Mar 7.
Abstract (Expand)
Authors: M. Krawczyk, H. Bantel, M. Rau, J. M. Schattenberg, F. Grunhage, A. Pathil, M. Demir, J. Kluwe, T. Boettler, S. N. Weber, A. Geier, F. Lammert
Date Published: 28th Feb 2018
Publication Type: Not specified
PubMed ID: 29483677
Citation: J Hum Genet. 2018 May;63(5):621-626. doi: 10.1038/s10038-018-0420-4. Epub 2018 Feb 26.
Abstract (Expand)
Authors: T. Cvitanovic, M. C. Reichert, M. Moskon, M. Mraz, F. Lammert, D. Rozman
Date Published: 19th May 2017
Publication Type: Not specified
PubMed ID: 28520105
Citation: Hepatology. 2017 May 18. doi: 10.1002/hep.29268.
Abstract (Expand)
Authors: M. Krawczyk, S. Zimmermann, G. Hess, R. Holz, M. Dauer, J. Raedle, F. Lammert, F. Grunhage
Date Published: 17th Mar 2017
Publication Type: Not specified
PubMed ID: 28301573
Citation: PLoS One. 2017 Mar 16;12(3):e0173506. doi: 10.1371/journal.pone.0173506. eCollection 2017.