Assay type 'Experimental Assay Type'

Data digitized from publication.

Hetzler1990 Description

Data digitized from publication.

Spigset1999a Description

Data digitized from publication.

Akinyinka2000 Description

Data digitized from publication.

Perera2011 Description

Data digitized from publication.

Amchin1999 Description

Data digitized from publication.

Oh2012 Description

Data digitized from publication.

Kakuda2014 Description

Data digitized from publication.

Haller2002 Description

Data digitized from publication.

Healy1991 Description

Data digitized from publication.

Blanchard1983a Description

Data digitized from publication.

Tanaka2014 Description

Data digitized from publication.

Kaplan1997 Description

Data digitized from publication.

Magnusson2008 Description

Data digitized from publication.

Jeppesen1996 Description

LMs were characterized in human liver tissue sections using immunohistochemistry and bioinformatic image analysis. Isolated cells were characterized in suspension using FACS analyses and in culture using

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: pericentral (CV)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; hepatic zone: pericentral (CV)

Automatically generated assay to host openbis files that are linked to the original OpenBIS experiment. Its content and linked data files will be updated by the system if automatic synchronization was selected.

Automatically generated assay to host openbis files that are linked to the original OpenBIS experiment. Its content and linked data files will be updated by the system if automatic synchronization was selected.

Automatically generated assay to host openbis files that are linked to the original OpenBIS experiment. Its content and linked data files will be updated by the system if automatic synchronization was selected.

Automatically generated assay to host openbis files that are linked to the original OpenBIS experiment. Its content and linked data files will be updated by the system if automatic synchronization was selected.

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: intermediate (IZ)

Transcriptomic analysis of hepatocytes captured by laser micro-dissection from hepatic zone: periportal (PP)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; hepatic zone: intermediate (IZ)

DNA-methylation at binding sites of uniformly expressed transcription factors in human hepatocytes ; periportal (PP)

exp assay I Lucarelli paper

The liver comprises the body´s largest pool of macrophages constituting approximately 80 % of all sessile tissue macrophages of the body. After liver damage monocyte-derived macrophages are recruited into the liver and were here affected by a micro milieu which is considerably influenced by hepatocytes. Up to now the complex network that determines the differentiation and function of liver macrophages and the impact of the intercellular communication between macrophages and the other parenchymal ...

We describe a distinct macrophage population, whose presence in the liver during homoeostasis depends on recruitment signals mediated by the chemokine receptor CCR2. The identified polarization state of this population closely resembles that induced in co-culture experiments, where hepatocytes are reducing the availability of TGFb to macrophages. Accordingly, disruption of TGFb signal transduction in macrophages phenocopies the influence of hepatocytes on macrophage polarization.

Transcriptomics: the RNA expression of primary hepatocytes and BMDM (Bone Marrow–Derived acrophages) were analysed in 4 different conditions (mono- vs. co-culture, hepatocytes and macrophages) with 5 replicas each to detect the impact of hepatocytes on macrophages and vice versa.

RNA sequence data

Western blot

DNA sequence data